Comparative Antioxidative Activities of Cratoxylum cochinchinense and Clinacanthus Nutans

Bok, Chui Yin (2019) Comparative Antioxidative Activities of Cratoxylum cochinchinense and Clinacanthus Nutans. Final Year Project (Bachelor), Tunku Abdul Rahman University College.

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Abstract

Cratoxylum cochinchinense and Clinacanthus nutans are the native species in Malaysia and they are being used as traditional medicines in the past. Studies have found that these plants possessed antimicrobial and antioxidant properties. In this research, the objective is to compare the antioxidant potentials and chemical constituents of the extract from different parts of Cratoxylum cochinchinense and Clinacanthus nutans. The methanolic extracts are tested to determine the total phenolic and flavonoids content using Folin-Ciocalteu and aluminium chloride colorimetric methods, respectively. On the other hand, the antioxidant potentials of the extracts are evaluated with various antioxidant assays such as DPPH and ABTS radical scavenging, ferric reducing antioxidant power (FRAP), and ferrous ion chelating activity assays. Results show that C. cochinchinense contains high phenolic and flavonoid content as compared to C. nutans. Furthermore, C. cochinchinense also demonstrates higher DPPH and ABTS radical scavenging activities than C. nutans. In addition, C. cochinchinense exhibits higher ability in reducing Fe3+ to Fe2+ than C. nutans. Nevertheless, C. nutans is a stronger ferrous ion chelator. In conclusion, C. cochinchinense possesses strong antioxidative activities with high phenolic and flavonoid content than C. nutans.