Biodegradable Elastomeric Polymers for Biomedical Applications

 




 

Tam, Siew Yin (2020) Biodegradable Elastomeric Polymers for Biomedical Applications. Final Year Project (Bachelor), Tunku Abdul Rahman University College.

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Abstract

Poly(glycerol-dodecanoate) (PGD) offer the greatest versatility as biomaterials and are frequently explored for tissue engineering applications. The physicochemical properties of PGD can be specifically tailored for implantable medical devices through modifying the cross-linking. PGD is synthesis from glycerol and dodecanedioic acid monomers through thermal condensation process. PGD is a smart polymer owing to its temperature responsive and shape memory properties. Besides, PGD is biodegradable and biocompatible and it is a nonconductive polyester. For the sake of making PGD more useful and valuable in biomedical applications especially in tissue engineering, a conductive polymers composite will be synthesized in this project by adding graphite into PGD, making PGD conductive. The effect of amount of graphite added will be studied. The characterization results proven that the amount of graphite filler has an effect on electrical conductivity properties, thermal properties of pure PGD as well as the shape memory effect. The electrical conductivity of samples is increased with the increased of conductive filler. Moreover, shape memory properties are highly dependent on cross linking level. Higher crystallinity or cross-linked samples will have higher degradation temperature as well as transformation temperature. In this case, pure PGD is having higher crystallinity and cross-linking level than the composites, hence, it has better thermal properties as well as shape recovery ratio than the composites. On the other hand, the conducting PGD composites are having better electrical conductivity as well as shape recovery rate and shape retention ratio as compared to pure PGD.

Item Type: Final Year Project
Subjects: Technology > Materials
Faculties: Faculty of Engineering and Technology > Bachelor of Material Engineering with Honours
Depositing User: Library Staff
Date Deposited: 24 Apr 2020 16:40
Last Modified: 22 Sep 2020 09:07
URI: https://eprints.tarc.edu.my/id/eprint/14425