Synthesis and Characterization Studies of the Novel 4-(P-Acetoxyphenyl)-2-Butanone 4-Methyl – 3-Thiosemicarbazone and Its Zinc (II) Complex

Ngan, Chun Wai (2021) Synthesis and Characterization Studies of the Novel 4-(P-Acetoxyphenyl)-2-Butanone 4-Methyl – 3-Thiosemicarbazone and Its Zinc (II) Complex. Final Year Project (Bachelor), Tunku Abdul Rahman University College.

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Abstract

Synthesis of novel thiosemicarbazide derived Schiff base by the condensation reaction of 4- methyl-3-thiosemicarbazide (4M3T) and 4-(p-acetoxyphenyl)-2-butanone (4ACT) was successfully carried out. The synthesized Schiff base, MT4ACT was reacted with transition metal acetate salt of Zn(II) yielding metal complexes with stoichiometry metal-ligand ratio of 1:2 with the formula of Zn(MT4ACT)2. These compounds were characterized by different analytical techniques, such as FTIR-ATR, 1H NMR, 13C NMR, MS and SXRD. The results showed that Schiff base behaved as a bidentate NS donor ligand and coordinated via the azomethine nitrogen and thiolate sulphur. The FTIR spectrum confirmed that the ligand existed in thione form in solid state. Furthermore, the NMR spectrum confirmed that the ligand existed in thione form in solution state. The stoichiometry concluded from the analytical data was in good agreement with the proposed formula of the ligand and metal complexes.