Late Chronotype, Its Association With Glycemic Tolerance in Non-Shift Working Diabetes and Prediabetes Adults in Asia: a Scoping Review

Lem, June Ee Mun (2022) Late Chronotype, Its Association With Glycemic Tolerance in Non-Shift Working Diabetes and Prediabetes Adults in Asia: a Scoping Review. Final Year Project (Bachelor), Tunku Abdul Rahman University College.

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Abstract

Human were embedded with a biological clock. It is activated by the sunlight exposure through eyeballs and begin our daily’s circadian rhythm. Two main chronotype discussed in this review which is morning chronotype and late chronotype. This review is to investigate the associations between chronotype and glucose tolerance among non-shift working prediabetes and diabetes adults in Asia. Misalignment of circadian rhythm is caused by disruption by socially cues. A systematic search was conducted on two database which are PubMed and Google Scholar. The inclusion criteria were prediabetic and diabetic adults in the range age of 20 to 90. A total of 10 studies were included in this review. Majority of these studies was based on a cross-sectional design (n=7). The factors affecting blood glucose level is due to their sleeping pattern, inappropriate meal time, midday naps, obstructive sleep apnea, gender and age. The scoping review demonstrates that evening chronotype prediabetic and diabetic patients are mostly engaged with poor glycemic control, significantly associated with high blood glucose, and high HbA1c. Thus, this type of chronotype have increase the risk of type 2 diabetes or aggravate the blood glucose level of a diabetic or a prediabetic adults. Hence, this review suggested that evening chronotype have greater risk of hyperglycemia