Green Synthesis and Characterization of Ag2S/Fe3O4 Nanocomposite and Evaluation of Its Antibacterial Properties in the Form of a Topical Cream

Choo, Kristie Yin Zhen (2023) Green Synthesis and Characterization of Ag2S/Fe3O4 Nanocomposite and Evaluation of Its Antibacterial Properties in the Form of a Topical Cream. Final Year Project (Bachelor), Tunku Abdul Rahman University College.

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Abstract

This research project was carried out to synthesize and characterize Fe3O4/Ag2S nanocomposite and evaluate its antibacterial properties in the form of a topical cream. The goal of this research is to synthesize the Fe3O4/Ag2S nanocomposite via wet chemical reduction method and the decomposition of silver thiosulphate which is a new method that has not been reported yet, characterize the synthesized Fe3O4/Ag2S nanocomposite via combination of techniques such as TEM, SEM, XRD, EDX, VSM, and FTIR, synthesize Fe3O4/Ag2S cream and evaluate the antibacterial properties of the cream specifically on the Staphylococcus aureus bacteria. Fe3O4/Ag2S nanocomposite were synthesized by using wet chemical reduction method and decomposition of silver thiosulphate as this method is based on some of the principles in green chemistry and it does not harm the environment because the reaction was carried out in ambient temperature, it is a simple yet effective method and the Fe3O4/Ag2S nanocomposite synthesized are magnetically recoverable where it can be recaptured and recycled in wastewater treatments hence it would not persist in the environment. Furthermore, the antibacterial properties of the Fe3O4/Ag2S cream were carried out via agar diffusion method specifically on the Staphylococcus aureus bacteria. A new green synthesis for Fe3O4/Ag2S nanocomposite was successfully developed in nanoscale with good crystallinity and superparamagnetic properties. The Fe3O4/Ag2S cream (1%) could inhibit the Staphylococcus aureus bacteria, but further work is required to increase the dose of Ag2S while maintaining superparamagnetic properties. Dermatological test is required for future commercialization of the antibacterial Fe3O4/Ag2S cream. Lastly, magnetically recoverable nanocomposite in cream could help achieve Environment Social Governance (ESG) that businesses need to achieve